113days until
Primary MCQ 15/08/2014

146days until
Primary VIVA 17/09/2014

Normal Cell and Cellular Injury

These are the first 2 topics on the Pathology MCQ matrix at 2 MCQs for normal and 3 MCQs for injury
 
The path Syllabus now says:
  • 1. CELLULAR INJURY AND ADAPTATION 2
        1.1 Cellular adaptation 1
        1.2 Mechanism of cell injury 1
i.e. The College has removed the "Normal Cell" that used to be the first part of the Pathology syllabus.

I still feel that understanding Physiology "building block" concepts and the  "Principles of cellular function" before tackling cellular level pathology is important but they are now only found in the Physiology Syllabus.

 
Robbins says:


1. Cellular Responses to Stress & Toxins............................................................... 15
    Introduction to Pathology ..................................................................................... 15
    Overview: Cellular Responses to Stress & Noxious Stimuli .................................... 17
    Adaptations of Cellular Growth & Differentiation ..................................................... 21
    Overview of Cell Injury & Cell Death ..................................................................... 29
    Causes of Cell Injury ........................................................................................... 30
    Morphologic Alterations in Cell Injury .................................................................... 32
    Mechanisms of Cell Injury ................................................................................... 43
    Clinico-Pathologic Correlations: Selected Examples of Cell Injury & Necrosis .......... 56
    Apoptosis .......................................................................................................... 59
    Autophagy ......................................................................................................... 72
    Intracellular Accumulations .................................................................................. 73
    Pathologic Calcification ....................................................................................... 83
    Cellular Aging ..................................................................................................... 86

consider aiding your reading with the read-along Robbins version on youtube:
 
There is also a series of lectures online:
 
And as of the first sitting 2010 it also references
 
GANONG (I presume it's for chapter one)
  1. The general & cellular basis of medical physiology
I still don't think it's quite as nice as GUYTON Ch.2 - The cell and its functions

Amit says:

  • Definitions of hypertrophy, hyperplasia, atrophy, metaplasia, dysplasia,

  • Describe mechanisms of cell inj. and death

  • Describe morphology of reversible and irreversible injury

  • What is apoptosis, and describe its mechanism, and morphology

  • Describe different types of necrosis, with examples, and morphology

  • What is the mechanism of reperfusion injury

     

This is a classic "Question 1" for the path component of the exam...
2011-1-3-1    Cell death/necrosis
2011-1-2-1    Atrophy
2011-1-1-1    Ischaemic cell injury
2010-2-2-1    Hypertrophy
2010-1-3-1    Hypertrophy
2010-1-2-1    Metaplasia
2010-1-1-1    Reperfusion injury
2009-2-3-1    Reversible versus irreversible cellular injury
2009-1-2-1    Cellular changes following ischemia
2008-2-1-1    Ischemic injury
2008-1-2-1    Apoptosis
2008-1-1-1    Hypertrophy vs. Hyperplasia
2007-2-1-1    Metaplasia
2007-1-3-1    Hypertrophy
2007-1-2-1    Atrophy
2007-1-1-1    Hyperplasia
2006-2-3-1    Apoptosis
2006-2-2-1    Reperfusion injury
2006-1-2-1    Reversible vs. irreversible ischaemic change
2006-1-1-1    Reperfusion injury
 
 
Comments